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I-Mab Ok'd to Start China Trials of CD47 Immunotherapy

publication date: Jul 16, 2019

I-Mab Biopharma of Shanghai announced China approval to begin Phase I trials of its fully human CD47 mAb, which was developed to treat malignant tumors. Earlier this year, I-Mab was granted a similar approval in the US and reported the first patient dosing in June. I-Mab believes TJC4 has the potential to become a global best-in-class CD47 product because it binds to a unique epitope on CD47. This leads to minimal red blood cell binding, which allowed the molecule to avoid hemagglutination and anemia in preclinical tests. More details....

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