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Adagene Reports Positive Early Results from its anti-CTLA-4 for Colorectal Cancer

publication date: Jan 17, 2024

Suzhou Adagene reported positive early data from a US Phase Ib/II trial of its masked anti-CTLA-4 SAFEbody® ADG126 (muzastotug) in patients with Metastatic Microsatellite-stable (MSS) Colorectal Cancer (CRC). Adagene’s masking technology allows higher, more frequent dosing with better safety, which the company believes will result in a best-in-class candidate. The trial administered ADG126 at a rate of up to 200mg every three weeks in combination with Merck’s anti-PD-1 therapy Keytruda® every three weeks in heavily pretreated patients. The regimen produced a best-in-class safety profile. More details....

Stock Symbol: (NSDQ: ADAG)

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