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Antengene to Start Trial of I PAK4/NAMPT Inhibitor in Solid Tumors/NHL

publication date: Apr 7, 2021

Shanghai Antengene was approved to start a China Phase I clinical trial of ATG-019 in patients with advanced solid tumors or non-Hodgkin's lymphoma (NHL). ATG-019 is a novel oral dual PAK4/NAMPT inhibitor that will be administered as a monotherapy or combined with niacin ER. In preclinical tests, ATG-019 showed anti-tumor activity and a superior pharmacokinetics (PK) and safety profile, the company said. Antengene has a Taiwan Phase I clinical trial of ATG-019 underway in the same patient population. More details....

Stock Symbol: (HK: 6996)

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