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Ascentage Pharma to Start Phase III Trial of Bcl-2 Inhibitor for Leukemia

publication date: Oct 13, 2023

Suzhou Ascentage Pharma was approved to start a pivotal global Phase III study of its Bcl-2 inhibitor APG-2575 (lisaftoclax) as a first-line therapy for lymphocytic leukemia. The candidate will be administered in combination with AstraZeneca’s acalabrutinib, a BTK inhibitor, and compared to immunochemotherapy for efficacy and safety. Patients will have either chronic lymphocytic leukemia or small lymphocytic leukemia. In August, Ascentage was approved to conduct a US Phase III trial of the Bcl-2 inhibitor in patients with CLL/SLL who have received prior therapies. More details....

Stock Symbol: (HK: 6855)

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