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Asieris Starts China Trials of Dopamine Beta-Hydroxylase Inhibitor for Ulcerative Colitis

publication date: Aug 30, 2023

Shanghai Asieris Pharma will start China trials of oral APL-1401 for patients with moderately-to-severely active ulcerative colitis. APL-1401 is a dopamine beta-hydroxylase (DβH) inhibitor. Inflammatory bowel diseases are associated with altered neuronal regulation of the gastrointestinal tract and release of norepinephrine (NE). Because sympathetic stimulation of the GI tract modulates immune function, changes in NE signaling may alter the risk of developing bowel disease. Asieris, which was previously approved to start US trials of APL-1401, develops drugs for genitourinary tumors and other related diseases. More details....

Stock Symbol: (SHA: 688176)

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