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AusperBio Updates Clinical Progress of Antisense Oligonucleotide Therapy for HBV

publication date: Feb 15, 2024

AusperBio, a Hangzhou-San Francisco biopharma, reported its lead candidate, AHB-137, an unconjugated antisense oligonucleotide (ASO) that targets all HBV RNA, is advancing through clinical trials in China and the US. The company believes AHB-137 will prove to be a functional cure for chronic hepatitis B. The candidate is a product of AusperBio’s proprietary Med-OligoTM ASO platform, which the company expects will produce more effective therapies than available ASO offerings. Currently, two Phase Ia/Ib clinical trials, one in China and the other in the US/New Zealand, have dosed 122 participants, including 30 CHB patients. More details....

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