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CANbridge to Start Trial of Novel Complement Dysfunction Therapy

publication date: Dec 18, 2020

Beijing CANbridge Pharma, a rare disease company, announced approval to start Singapore clinical trials of its monoclonal antibody targeting complement C5 of the complement system. The first trial for CAN106 will be in patients with paroxysmal nocturnal hemoglobinuria (PNH), a fatal disease in which the complement system destroys red blood cells. As part of an immune response, the complement system helps antibodies and phagocytic cells clear microbes and damaged cells. Dysregulation of the system leads to several rare diseases, including PNH. More details....

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