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CARsgen Cleared to Stage China Trial of CAR-T for Hepatocellular Carcinoma

publication date: Jan 18, 2024

Shanghai CARsgen Therapeutics was cleared to start a China trial of CT011, an autologous CAR T-cell candidate against Glypican-3 (GPC3) for hepatocellular carcinoma. Patients must have GPC3-positive stage IIIa disease with a high risk of recurrence following surgical resection. CT011 is an autologous GPC3 CAR T-cell product that was originally cleared by China’s NMPA in 2019 to treat patients with GPC3-positive solid tumors, the first China CAR T-cell therapy clearance for a solid tumor indication. CARsgen has completed enrollment of a China Phase I trial for the candidate. More details....

Stock Symbol: (HK: 2171)

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