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Gritgen’s Gene Therapy for Hemophilia 100% Effective in IIT Trial

publication date: Nov 16, 2023

Suzhou Gritgen Therapeutics reported its novel gene therapy for Hemophilia A (HA) posted 100% effective results in the first 12 weeks following treatment. The Investigator Initiated Trial enrolled 12 patients with severe HA whose endogenous factor VIII (FVIII) activity was lower than 1%. All patients were treated with a single dose of GS1191 by mid-May. Currently, all patients enrolled in the high dose group have normal FVIII activities with no bleeding episodes observed. Gritgen has begun its own China Phase I trial of GS1191 in patients with severe HA. More details....

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