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Harbour BioMed to Start US Trials of its First ADC Candidate

publication date: Aug 29, 2023

Harbour BioMed was approved to start US clinical trials of its first antibody drug conjugate candidate, HBM9033, which targets human mesothelin (MSLN). MSLN is a tumor associated antigen that is upregulated in various solid tumors. The fully human monoclonal antibody in HBM9033 binds preferably to membrane bond MSLN over soluble MSLN, minimizing the interference of shedding MSLN on the binding and internalization of membrane bond MSLN. In preclinical tests, HBM9033’s unique mAb and linker-payload have shown best-in-class potency and safety, according to HBM. HBM has operations in Cambridge, MA, Rotterdam and Suzhou. More details....

Stock Symbol: (HK: 02142)

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