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Harbour Biomed to Start US Trials of Novel B7H7 Immunoncology Asset

publication date: Jan 13, 2023

Harbour Biomed was cleared to start US Phase I trial of its novel, fully human mAb targeting B7H7 in patients with advanced solid tumors. The company points out that B7H7 is part of the B7 family, which has provided many successful immunoncology drugs, including PD-L1 and CTLA-4 drugs. Harbour says the candidate does not overlap with PD-L1 expression in multiple tumor types, implying it targets a different immune evasion pathway than PD-L1, which could benefit PD-L1 negative/refractory patients. Harbour is headquartered in Cambridge, MA, with drug discovery operations in Rotterdam and an R&D lab in Suzhou. More details....

Stock Symbol: (HK: 02142)

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