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Hengrui Sells PARP1 Inhibitor to Germany’s Merck in $1.7 Billion Deal

publication date: Oct 30, 2023

Jiangsu Hengrui Pharma out-licensed global rights (ex-China) for its next-gen PARP1 inhibitor to Germany’s Merck KGaA for a $170 million upfront payment and up to $1.5 billion in milestones, plus royalties. Merck will have rights to manufacture and commercialize the drug. It will also have an option for exclusive global rights to manufacture and commercialize Hengrui’s Claudin-18.2 antibody-drug conjugate (ADC) SHR-A1904. And Merck will own an option to co-promote both assets in China. Hengrui says next-gen PARP1 inhibitors offer better selectivity and safety, offering possible efficacy in new indications. More details....

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