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I-Mab Approved to Start China Trials of CD73 Antibody

publication date: Oct 4, 2019

I-Mab Biopharma, a Shanghai-US company developing novel biologics, was granted China approval to start clinical trials of TJD5, a novel CD73 antibody, in patients with advanced solid tumors. I-Mab says TJD5 blocks CD73, a surface enzyme on stromal and cancer cells that causes the production of adenosine, a highly immunosuppressive nucleoside. Previously, the candidate started a Phase I clinical trial in the US to assess the safety and efficacy of TJD5, both as a single agent and in combination with PD-1/PD-L1 products. More details....

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