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Beijing InnoCare Plans Combined Therapy with Arrivent for NSCLC

publication date: Jul 14, 2023

Beijing InnoCare Pharma forged a clinical development collaboration with ArriVent, a Philadelphia area biopharma, to test a combination drug regimen for advanced non-small cell lung cancer. The trial will evaluate a combination of InnoCare’s novel SHP2 allosteric inhibitor, ICP-189, with ArriVent’ s furmonertinib, a highly brain-penetrant, broadly active mutation-selective EGFR inhibitor. InnoCare’s ICP-189 SHP2 mediates the MAPK signaling pathway and immune checkpoint pathway. In preclinical tests, it has shown better selectivity than other phosphatases, demonstrating significant anti-tumor effects in several xenograft models, InnoCare says. More details....

Stock Symbols: (HK: 09969; SHA: 688428)

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