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Legend Halts US Trial of CD4+ CAR-T after First Patient Dosed

publication date: Feb 18, 2022

Nanjing Legend Biotech announced the US FDA put a clinical hold on an early stage CAR-T therapy after the first patient was dosed. LB1901 is an autologous CAR-T therapy targeting malignant CD4+ T-cells. It is being tested in patients with relapsed or refractory T-cell lymphoma (TCL). After noticing the patient had low CD4+ T-cell counts, Legend paused the clinical trial and notified the FDA. The patient has not experienced any drug-related serious adverse events. More details....

Stock Symbol: (NSDQ: LEGN)

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