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Ractigen Files to Start Australian Trials of saRNA Therapy for Bladder Cancer

publication date: Dec 6, 2023

Jiangsu Ractigen Therapeutics filed an IND in Australia to start clinical trials of its lead small acting RNA (saRNA) product in patients with non-muscle-invasive bladder cancer who did not respond to Bacillus Calmette-Guérin therapy. RAG-01 targets and activates the tumor suppressor gene p21. The Phase Ⅰ, open-label, multi-center study will evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of RAG-01, which is Ractigen’s first clinical stage product and the first saRNA candidate from a Chinese company to start trials. More details....

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