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SineuGene Reports Positive Initial Results of RNA Therapy for ALS

publication date: Jan 19, 2024

SineuGene, a Beijing startup that is developing an RNA therapy for ALS, reported that its lead candidate, SNUG01, slowed the progression of ALS to a “plateau stage” in the first person dosed with the therapy. In addition, the patient’s lower limbs responded to electric stimulation, an indication that a nerve has at least partly rejuvenated. SineuGene is led by Yichang Jia, PhD, a Professor at Tsinghua University School of Medicine. The company has not disclosed many details about its research, but its lead candidate stems from his research into RNA metabolism abnormalities that cause ALS. SineuGene believes its technology may also be effective for two other brain maladies, Alzheimer’s and Parkinson’s. More details....

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