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TransThera to Start European Arm of Global Trial for Bile Tube Cancer

publication date: Mar 8, 2024

Nanjing TransThera was approved to begin a European Phase III trial of tinengotinib in patients with cholangiocarcinoma (CCA). CCA, a cancer in the tubes that carry the digestive fluid bile through the liver, is a rare but aggressive form of cancer. To be enrolled, patients must have FGFR-altered disease that is refractory/relapsed from chemotherapy or a FGFR Inhibitor. The European Phase III trial is part of a global study of the drug. Tinengotinib, a next-gen FGFR inhibitor, has shown potency against a variety of FGFR2 kinase domain mutations in Phase I and II trials for the CCA indication. More details....

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